High-Protein Cottage Cheese Zucchini Pizza Casserole (Low-Carb)

High-Protein Cottage Cheese Zucchini Pizza Casserole (Low-Carb)

This casserole delivers pizza flavors with plenty of protein and far fewer carbs than traditional pizza. Cottage cheese adds creaminess and protein, while zucchini replaces most of the starch.

Yield

  • 6–8 servings

Prep Time

  • 20 minutes

Cook Time

  • 40–45 minutes

Total Time

  • About 1 hour

Approximate Nutrition (Per Serving, 8 Servings)

  • Calories: 250–320
  • Protein: 22–28 g
  • Net Carbs: 5–8 g
  • Fat: 12–18 g

Ingredients

Zucchini Base

  • 4 medium zucchini (about 2 lb / 900 g)
  • 1 tsp salt

Protein Layer

  • 2 cups (450 g) low-fat cottage cheese
  • 2 large eggs
  • 1 cup (100 g) shredded mozzarella cheese
  • ¼ cup (25 g) grated Parmesan cheese
  • 1 tsp Italian seasoning
  • ½ tsp garlic powder
  • ¼ tsp black pepper

Meat Layer

  • 1 lb (450 g) lean ground turkey, chicken, or beef
  • 1 tsp olive oil
  • ½ small onion, finely diced
  • 2 cloves garlic, minced

Sauce Layer

  • 1 cup (240 ml) pizza sauce or marinara sauce
  • 1 tsp Italian seasoning

Topping

  • 1½ cups (170 g) shredded mozzarella cheese
  • 20–25 turkey pepperoni slices or regular pepperoni
  • 2 tbsp grated Parmesan

Optional toppings:

  • Mushrooms
  • Bell peppers
  • Black olives
  • Jalapeños

Step 1: Prepare the Zucchini

  1. Slice zucchini into thin rounds (about ¼ inch / 6 mm thick).
  2. Place in a colander.
  3. Sprinkle with 1 tsp salt.
  4. Let sit for 20 minutes.

This removes excess moisture.

Pat dry thoroughly with paper towels.


Step 2: Cook the Meat

Heat olive oil in a skillet over medium heat.

Add:

  • Onion
  • Garlic

Cook 2–3 minutes.

Add ground meat.

Cook until browned and fully cooked.

Drain excess liquid if needed.

Set aside.


Step 3: Make the Cottage Cheese Mixture

In a large bowl combine:

  • Cottage cheese
  • Eggs
  • 1 cup mozzarella
  • ¼ cup Parmesan
  • Italian seasoning
  • Garlic powder
  • Black pepper

Mix well.


Step 4: Preheat the Oven

Preheat oven to 375°F (190°C).

Lightly grease a 9×13-inch (23×33 cm) baking dish.


Step 5: Build the First Layer

Arrange half of the zucchini slices across the bottom of the dish.

Slight overlapping is fine.


Step 6: Add the Protein Layer

Spread the cottage cheese mixture evenly over the zucchini.

Use a spatula to smooth it out.


Step 7: Add the Meat Layer

Spread the cooked meat evenly over the cottage cheese mixture.


Step 8: Add Remaining Zucchini

Arrange the remaining zucchini slices over the meat layer.


Step 9: Add Sauce

Mix pizza sauce with Italian seasoning.

Spread evenly across the top.


Step 10: Add Cheese and Toppings

Top with:

  • 1½ cups mozzarella
  • 2 tbsp Parmesan
  • Pepperoni slices
  • Any additional toppings

Step 11: Bake

Bake uncovered for 35–45 minutes.

The casserole is done when:

  • Cheese is melted and golden
  • Edges are bubbling
  • Center is set

If the top browns too quickly, loosely tent with foil.


Step 12: Rest Before Serving

Allow the casserole to rest for 10–15 minutes before slicing.

This helps it firm up and makes serving easier.


Extra-High-Protein Version

To boost protein even further:

  • Use 1½ lb (680 g) lean ground turkey or chicken.
  • Add 1 cup liquid egg whites to the cottage cheese mixture.
  • Increase cottage cheese to 3 cups.
  • Increase mozzarella by ½ cup.

This can raise protein to approximately 30–35 g per serving.


Meal Prep & Storage

Refrigerator

  • Store covered for up to 4 days.

Freezer

  • Freeze portions individually for up to 3 months.

Reheating

  • Microwave: 2–3 minutes.
  • Oven: 350°F (175°C) for 15–20 minutes.

Serving Ideas

  • Side salad with vinaigrette
  • Roasted broccoli
  • Garlic green beans
  • Sautéed spinach

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